Hong-Gyum Kim 教授
Hong-Gyum Kim, 1972年生,国籍韩国,1997年毕业于韩国江源大学,2004年在江源大学获分子生物学博士学位。2001年起,先后担任江源大学教学助理、学位研究助理、PhiloBiotech公司研究助理、江源大学讲师、博士后研究员、荷美尔研究院博士后研究员、研究助理、研究助理教授。2015年起任中美(河南)荷美尔肿瘤研究院PI。
成员资格:
2008-2010年 美国癌症协会会员
1997-2005年 韩国生物化学与分子生物学学会成员
1997-2005年 韩国分子生物学与细胞生物学学会成员
1997-2004年 美国微生物学会成员
所获奖项:
2004.2 Award of Prime Research Paper in Kangwon NationalUniversity
2001.11 - 2002.10 Research Fund from the Korea Research Foundation
发表论文(部分):
1. Kim HG, Shi CC, Bode AM, Dong Z (2015) p38a MAPK is required for arsenic-induced cell transformation. Mol. Carcinog. (Epub.)
2. Chen H, Yao K, Chang X, Shim JH,Kim HG, Malakhova M, Kim DJ, Bode AM, Dong Z (2015)Computational and Biochemical Discovery of RSK2 as a Novel Target for Epigallocatechin Gallate (EGCG).PLoS One (eCollection)
3. Yao K,Chen H,Liu K,Langfald A,Yang G,Zhang Y,Yu DH,Kim MO,Lee MH,Li H,Bae KB,Kim HG,Ma WY,Bode AM,Dong Z,Dong Z (2014) Kaempferol Targets RSK2 and MSK1 to Suppress UV Radiation-Induced Skin Cancer. Cancer Prev. Res. 9, 958-967.
4. Liu K, Park C, Chen H, Hwang J, Thimmegowda NR, Bae EY, Lee KW,Kim HG, Liu H, Soung NK, Peng C, Jang JH, Kim KE, Ahn JS, Bode AM, Dong Z, Kim BY, Dong Z (2014)Eupafolin suppresses prostate cancer by targeting phosphatidylinositol 3-kinase-mediated Akt signaling. Mol. Carcinog.(Article first published online: 4 Apr. 2014, DOI: 10.1002/mc.22139)
5. Fu Y, Yang G, Zhu F, Peng C, Li W, Li H,Kim HG, Bode AM, Dong Z, Dong Z (2014) Antioxidants decrease the apoptotic effect of 5-FU in colon cancer by regulating Src-dependent capase-7 phosphorylation. Cell Death Dis. 5, e983.
6. Keum YS,Kim HG, Bode AM,Surh YJ and Dong Z (2013) UVB-induced COX-2 expression requires histone H3 phosphorylation at Ser10 and Ser28.Oncogene32, 444-452.
7. Kim HG, Kim DJ, Li S, Lee KY, Li X, Bode AM, Dong Z (2012)Polycomb (PcG) Proteins, BMI1 and SUZ12, Regulate Arsenic-induced Cell Transformation.J. Biol. Chem. 287, 31920-31928.
8. Lau AT, Lee SY, Xu YM, Zheng D, Cho YY, Zhu F,Kim HG, Li SQ, Zhang Z, Bode AM, Dong Z (2011)Phosphorylation of Histone H2B Serine 32 Is Linked to Cell Transformation.J. Biol. Chem. 286, 26628-26637.
9. Li X, Wen W, Liu K, Zhu F, Malakhova M, Peng C, Li T,Kim HG, Ma W, Cho YY, Bode AM, Dong Z, Dong Z (2011)Phosphorylation of Caspase-7 by p21-activated Protein Kinase (PAK) 2 Inhibits Chemotherapeutic Drug-induced Apoptosis of Breast Cancer Cell Lines.J. Biol. Chem. 286, 22291-22299.
10. Lee SY, Lau ATY, Jeong CH, Shim JH,Kim HG, Kim JB,Bode AM and Dong Z (2010) Histone XH2AX is required for xenopus anterior neural development: the critical role of threonine 16 phosphorylation. J. Biol. Chem. 285, 29525-29534.
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