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Mee-Hyun Lee教授

 

Mee-Hyun Lee,女,国籍韩国。2009毕业于韩国首尔大学药学院,专业医药生物科学。1996-1998年任韩国忠南大学自然科学学院助教。1998–2004年韩国C&C研究所担任高级研究员,2009-2010年在韩国首尔大学任高级研究员。2015年起任中美(河南)荷美尔肿瘤研究院PI。

获奖经历: 

1. Young Investigator Awards (2007) 3rd International Conference on Polyphenols and Health (ICPH 2007) (Nov. 25-28, Kyoto, Japan)

2. Best poster presentation award (2007) The Pharmaceutical Society of Korea, Spring meeting (May 11 12, Gwang-ju, Republic of Korea)

3. Scholars in Training Award: ITO EN foundation (2007) The 99th Annual meetings of American Association of Cancer Research (AACR) (Apr. 14 - 18, Los Angeles, CA, USA)

4. Best oral presentation award (2013) The Korean Society of Cancer Prevention, Osaek Symposium (July 12-13, Gangwon-do, Republic of Korea)

发表论文:

1. Eunmiri Roh, Tatyana Zykova, Mee-Hyun Lee, Janis Nadas, Feng Zhu, Yan Li, Hong-Gyum Kim, Young-Yeon Cho, Mi Hee Park, Ki Beom Bae, Tae-Gyu Lim, Ann M. Bode and Zigang Dong, PRPK is a novel therapeutic target and prognostic marker regulated by TOPK in skin cancer. Submitted in Nature Communications (IF: 10.742)

* Eunmiri Roh, Tatyana Zykova and Mee-Hyun Lee were equally contributed

2. Sung Keun Jung, Su Jeong Ha, Chang Hwa Jung, Yun Tai Kim, Hoo-Keun Lee, Myoung Ok Kim, Mee-Hyun Lee, Madhusoodanan Mottamal, Ann M Bode, Ki Won Lee and Zigang Dong, Naringenin targets ERK2 and suppresses UVB-induced photoaging. Submitted in Journal of Nutritional Biochemistry (IF: 4.592)

3. Mee-Hyun Lee, Myoung Ok Kim, Sung-Young Lee, Do Young Lim, Jae Young Kim, Sung-Hyun Kim, Dong Joon Kim, Sung Keun Jung, Ke Yao, Joydeb Kumar Kundu,  Hye Suk Lee, Cheol-Jung Lee, Sally E. Dickinson, David Alberts, G. Timothy Bowden, Steven Stratton, Clara Curiel, Janine Einspahr, Ann M. Bode, Young-Joon Surh, Yong-Yeon Cho and Zigang Dong, Genetic ablation of caspase-7 promotes solar simulated light-induced mouse skin carcinogenesis: the involvement of keratin-17. Submitted in Carcinogenesis (IF: 5.266)

4. Sung Keun Jung, Mee-Hyun Lee, DoYoung Lim, Sung Young Lee, Chul-Ho Jeong, Jong Eun Kim, Tae Gyu Lim, Hanyong Chen, Ann M. Bode, Hyong Joo Lee, Ki Won Lee, and Zigang Dong, 2015 Butein, a Novel Dual Inhibitor of MET and EGFR, Overcomes Gefitinib-Resistant Lung Cancer Growth. Molecular Carcinogenesis 54:322331 (IF: 4.770)

* Sung Keun Jung and Mee-Hyun Lee were equally contributed

5. Sung Keun Jung, Mee-Hyun Lee, Do Young Lim, Jong Eun Kim, Puja Singh, Sung-Young Lee, Chul-Ho Jeong, Tae-Gyu Lim, Hanyong Chen, Young-In Chi, Joydeb Kumar Kundu, Nam Hyouck Lee, Charles C. Lee, Yong-Yeon Cho, Ann M. Bode, Ki Won Lee, and Zigang Dong, 2014 Isoliquiritigenin Induces Apoptosis and Inhibits Xenograft Tumor Growth of Human Lung Cancer Cells by Targeting Both Wild Type and L858R/T790M Mutant EGFR. The Journal of Biological Chemistry 289:3583935848 (IF: 4.600)

* Sung Keun Jung and Mee-Hyun Lee were equally contributed

6. Mee-Hyun Lee, Joydeb Kumar Kundu, Young-Sam Keum, Yong-Yeon Cho, Young-Joon Surh and Bu Young Choi, 2014 Resveratrol Inhibits IL-6-Induced Transcriptional Activity of AR and STAT3 in Human Prostate Cancer LNCaP-FGC Cells. Biomolecules & Therapeutics 22: 426-430 (IF: 0.841)

* Mee-Hyun Lee and Joydeb Kumar Kundu were equally contributed

7. Ke Yao, Hanyong Chen, Kangdong Liu, Alyssa Langfald, Ge Yang, Yi Zhang, Dong Hoon Yu, Myoung Ok Kim, Mee-Hyun Lee, Haitao Li, Ki Beom Bae, Hong-Gyum Kim, Wei-Ya Ma, Ann M. Bode, Ziming Dong, and Zigang Dong, 2014 Kaempferol Targets RSK2 and MSK1 to Suppress UV Radiation-Induced Skin Cancer. Cancer Prevention Research 7:95867 (IF: 5.269)

8. Cheol-Jung Lee, Mee-Hyun Lee, Yong-Yeon Cho, 2014 Fibroblast and Epidermal Growth Factors Utilize Different Signaling Pathways to Induce Anchorage-independent Cell Transformation in JB6 Cl41 Mouse Skin Epidermal Cells. Journal of Cancer Prevention 19:199-208

* Cheol-Jung Lee and Mee-Hyun Lee were equally contributed

9. Soouk Kang, Jong-Eun Kim, Nu Ry Song, Sung Keun Jung, Mee-Hyun Lee, Jun Seong Park, Myeong-Hun Yeom, Ann M. Bode, Zigang Dong, Ki Won Lee, 2014 The Ginsenoside 20-O-b-D-Glucopyranosyl-20(S)-Protopanaxadiol Induces Autophagy and Apoptosis in Human Melanoma via AMPK/JNK Phosphorylation. PLoS One 9:e104305 (IF: 3.534)

10. Do Young Lim, Mee-Hyun Lee, Seung Ho Shin, Hanyoung Chen, Joohyun Ryu, Lei Shan, Honglin Li, Ann M. Bode, Wei-Dong Zhang, and Zigang Dong, 2014 (+)-2-(1-Hydroxyl-4-Oxocyclohexyl) Ethyl Caffeate Suppresses Solar UV-Induced Skin Carcinogenesis by Targeting PI3K, ERK1/2, and p38. Cancer Prevention Research 7: 856865 (IF: 5.269)

 

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